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About m:Explorer

Welcome to m:Explorer! m:Explorer is a computational method for linking gene regulators and biological processes, using statistical analysis of high-throughput genomic data. Some of the method's predictions have been validated experimentally in the important model organism budding yeast (S.cerevisiae).
The method and the experimental validation of yeast gene regulators is a collaborative effort between the University of Tartu Department of Computer Science, Department of Molecular and Cell Biology (Estonia) and EMBL European Bioinformatics Institute (United Kingdom). The primary contributors include Jüri Reimand, Anu Aun, Jaak Vilo, Juan M. Vaquerizas, Juhan Sedman and Nicholas M. Luscombe. Tambet Arak has been helpful in setting up our homepage.

m:Explorer paper was published in Genome Biology:

Jüri Reimand, Anu Aun, Jaak Vilo, Juan M. Vaquerizas, Juhan Sedman, Nicholas M. Luscombe m:Explorer - multinomial regression models reveal positive and negative regulators of longevity in yeast quiescence (2012) Genome Biol 13:R55; doi: 10.1186/gb-2012-13-6-r55. [PDF]